RNA-Binding Proteins in Metazoans

Arin Ngamniyom, Thayat Sriyapai


RNA-binding proteins (RBPs) are the proteins which associate with RNAs in cells and play an important role in post-transcriptional process to create the spatiotemporal diversity of proteome in muticellular organisms.  They recognize specific sequence in the RNA stretch and are tissue-specific transcription of alternative splicing.   In all metazoans, RBPs regulate and control gene expressions by promoting or repressing mRNA targets in many tissues; examples include brain, heart, gonads bone and muscle.  Therefore, the aim of present paper is the subject to document and summarize the recent information and basic mechanisms of RBPs in metazoans.


RNA-binding proteins; alternative splicing; metazoans


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